Content: HERV-W gene family characterization.
Content: Characterization of the function and localization of HERV-W Env in human placenta. Identification of receptor interacting with Env.
Content: Identification of the fusogenic activity of syncytin-1.
Content: Detection of three putative HERV-W gag, pro, and env ORFs on chromosomes 3, 6, and 7. HERV-W env ORF, located on chromosome 7, is unique and encodes a putative 80-kDa glycosylated protein.
Content: Decreased syncytin-1 mRNA levels in PE and HELLP syndrome compared with normal placentas.
Content: HERV-W Env mRNA and glycoprotein expression are colinear with primary cytotrophoblast differentiation and with syncytiotrophoblast formation. A role of syncytin-1 in human trophoblast cell fusion and differentiation.
Content: Characterization of syncytin-1 synthesis and folding.
Content: Disruption of GCM1-transcription network and reduction in levels of syncytin-1 in PE.
Content: Comparison of ERVW-1/syncytin-1 and syncytin-2 expression levels in physiological and preeclamptic placentas, correlation with severity of preeclampsia.
Content: Comparison of ERVW-1/syncytin-1 expression levels in first trimester compared with term placentas. Altered ERVW-1/syncytin-1 expression in PE, IUGR, and PE with IUGR. Immunoreactivity of syncytin´s surface unit with fetal endothelium.
Content: Syncytin-1 detection in human placental exosomes.
Content: The review article about a role of syncytins in human.
Content: Abnormal ERVW-1/syncytin-1 expression in schizophrenia patients.
Content: IFN-induced transmembrane proteins (a family of restriction factors) impair syncytiotrophoblast formation and inhibit syncytin-mediated fusion.
Content: Effect of NPFF (Neuropeptide FF) on mRNA and protein levels of hCG β, syncytin-1, syncytin-2, and GCM1.